Article
Characterization of the bovine type I IFN locus: rearrangements, expansions, and novel subfamilies.
BMC genomics - 24 Apr 2009
Walker Angela M, Roberts R Michael
Abstract excerpt
BACKGROUND: The Type I interferons (IFN) have major roles in the innate immune response to viruses, a function that is believed to have led to expansion in the number and complexity of their genes, although these genes have remained confined to single chromosomal region in all mammals so far examined. IFNB and IFNE define the limits of the locus, with all other Type I IFN genes except IFNK distributed between...
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