Article
The assembly and characterisation of two structurally distinct cattle MHC class I haplotypes point to the mechanisms driving diversity.
Immunogenetics - 1 Sept 2015
Schwartz John C, Hammond John A
Abstract excerpt
In cattle, there are six classical MHC class I genes that are variably present between different haplotypes. Almost all known haplotypes contain between one and three genes, with an allele of Gene 2 present on the vast majority. However, very little is known about the sequence and therefore structure and evolutionary history of this genomic region. To address this, we have refined the MHC class I region in the...
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