Unraveling IGK locus in dog breeds: IMGT® new insights into canine immunogenetics.

doi:10.1093/nargab/lqag020

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Unraveling IGK locus in dog breeds: IMGT® new insights into canine immunogenetics.

NAR genomics and bioinformatics - 1 Mar 2026

Kustro Garnica Taismara, Papadaki Ariadni, Georga Maria, Zeitoun Guilhem, Jabado-Michaloud Joumana, Folch Géraldine, Giudicelli Véronique, Gonzalez Pablo, Lesbon Jéssika Cristina Chagas, Alves Talita Gabriela Luna, Fukumasu Heidge, Kossida Sofia

Abstract excerpt

Over thousands of years, selective breeding of domestic dogs (Canis lupus familiaris) has led to extensive genetic diversity, underscoring the need for refined genomic and immunogenetic investigations. This study presents a comprehensive analysis and biocuration of the immunoglobulin kappa light chain locus (IGK) across multiple dog breeds to identify breed-specific variations and assess their relevance to canine...

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PMID: 41737242
DOI: 10.1093/nargab/lqag020
PMCID: PMC12926714

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