Article
The allotypic patchwork pattern of the rabbit IGKC1 allele b5wf: genic exchange or common ancestry?
Immunogenetics - 1 Jan 1999
van der Loo W, Mougel F, Bouton C, Sanchez M S, Monnerot M
Abstract excerpt
The protein sequences of different alleles of the rabbit immunoglobulin IGKC1 gene can differ at more than 40% of the amino acid positions. This exceptional degree of allelic divergence raises questions concerning the causal underlying mechanisms. We report the DNA sequence of the coding region o...
Topics
- Alleles
- Amino Acid Sequence
- Animals
- Animals, Wild
- Antibodies, Monoclonal
- Base Sequence
- DNA
- Epitopes
- Evolution, Molecular
- Gene Conversion
- Genes, Immunoglobulin
- Molecular Sequence Data
- Point Mutation
- Rabbits
- Sequence Alignment
- Sequence Homology, Amino Acid
- Spain
- Species Specificity