Article
Detection of new allotypic variants of bovine λ-light chain constant regions in different cattle breeds.
Developmental and comparative immunology - 1 Jan 2012
Diesterbeck Ulrike S, Aboelhassan Dalia M, Stein Sina K, Czerny Claus-Peter
Abstract excerpt
In the cattle breeds German Black Pied (GBP), German Simmental (GS), Holstein Friesian (HF), Aubrac (A) three transcribed allotypic variants in isotype IGLC2 and five allotypic variants in isotype IGLC3 were identified. Substitutions within the putative interface to CH1 at position 11 and 79 were noted. In IGLC2(b), K79E led to a charge conversion. In IGLC3(b) and IGLC3(c), the E79N replacement removed the charge...
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