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Article

Biological effects of decreasingRBM15on chronic myelogenous leukemia cells

12 Apr 2012

Abstract excerpt

RNA binding motif protein 15 (RBM15) was originally described as a 5' translocation partner of the MAL gene in t(1;22)(p13;q13)infant acute megakaryocytic leukemia. Although previous investigations have shown that Rbm15 has broad regulatory effects within murine hematopoiesis through modulating Notch-induced transcriptional activation, which plays key roles in leukemogenesis, it is not clear what the functions of...

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PMID: 22497198
DOI: 10.3109/10428194.2012.684350

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