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Article

p15Ink4b: Dual function in myelopoiesis and inactivation in myeloid disease

30 Oct 2007

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Source

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Identifiers

PMID: 18029205
DOI: 10.1016/j.bcmd.2007.09.005

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Related research

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Click a neighbor to travelStep 1 · 12 closest

p15Ink4b: Dual function in myelopoiesis and inactivation in myeloid diseasePMID 18029205Read ↗

Methylation status of the p15INK4B gene in hematopoietic progenitors and peripheral blood cells in myelodysplastic syndromesSemantic proximity Read ↗

Myeloid-specific inactivation of p15Ink4b results in monocytosis and predisposition to myeloid leukemia.Semantic proximity Read ↗

Aberrant methylation and impaired expression of the p15INK4b cell cycle regulatory gene in chronic myelomonocytic leukemia (CMML)Semantic proximity Read ↗

Methylation of p15INK4B is common, is associated with deletion of genes on chromosome arm 7q and predicts a poor prognosis in therapy-related myelodysplasia and acute myeloid leukemiaSemantic proximity Read ↗

Hypermethylation of the Ink4b locus in murine myeloid leukemia and increased susceptibility to leukemia in p15(Ink4b)-deficient mice.Semantic proximity Read ↗

Germline RBBP6 mutations in familial myeloproliferative neoplasmsSemantic proximity Read ↗

PRDM16 isoforms differentially regulate normal and leukemic hematopoiesis and inflammatory gene signatureSemantic proximity Read ↗

Hypermethylation of the p15INK4B Gene in Myelodysplastic SyndromesSemantic proximity Read ↗

Methylation of the <i>p15</i><sup><i>INK4B</i></sup> gene in myelodysplastic syndrome: it can be detected early at diagnosis or during disease progression and is highly associated with leukaemic transformationSemantic proximity Read ↗

ISG15: A double edged sword in cancerSemantic proximity Read ↗

Methylation of the p15INK4b Gene in Myelodysplastic Syndromes Is Frequent and Acquired During Disease ProgressionSemantic proximity Read ↗

Tumor suppressor gene inactivation in myeloid malignancies.Semantic proximity Read ↗

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