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Article

ISG15: A double edged sword in cancer

1 Jun 2015

Abstract excerpt

) transcript is aberrantly expressed in most human malignancies, suggesting that it has a protumor function. However, at the protein level ISG15 has both protumor and immunomodulatory antitumor functions. Therapeutic strategies to maximize the latter may benefit cancer patients overexpressing the ISG15 pathway.

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Identifiers

PMID: 26587329
DOI: 10.1080/2162402x.2015.1052935

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

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