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Article

Genome-wide association analysis of radiation resistance in Drosophila melanogaster.

PloS one - 1 Jan 2014

Vaisnav Mahesh, Xing Chao, Ku Hung-Chih, Hwang Daniel, Stojadinovic Strahinja, Pertsemlidis Alexander, Abrams John M

Abstract excerpt

BACKGROUND: Ionizing radiation is genotoxic to cells. Healthy tissue toxicity in patients and radiation resistance in tumors present common clinical challenges in delivering effective radiation therapies. Radiation response is a complex, polygenic trait with unknown genetic determinants. The Drosophila Genetic Reference Panel (DGRP) provides a model to investigate the genetics of natural variation for sensitivity...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 25121966
DOI: 10.1371/journal.pone.0104858
PMCID: PMC4133248

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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