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Article

A genome-wide screen for genetic variants that modify the recruitment of REST to its target genes.

PLoS genetics - 1 Jan 2012

Johnson Rory, Richter Nadine, Bogu Gireesh K, Bhinge Akshay, Teng Siaw Wei, Choo Siew Hua, Andrieux Lise O, de Benedictis Cinzia, Jauch Ralf, Stanton Lawrence W

Abstract excerpt

Increasing numbers of human diseases are being linked to genetic variants, but our understanding of the mechanistic links leading from DNA sequence to disease phenotype is limited. The majority of disease-causing nucleotide variants fall within the non-protein-coding portion of the genome, making...

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Source

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Identifiers

PMID: 22496669
DOI: 10.1371/journal.pgen.1002624
PMCID: PMC3320604

Genes

REST
CDH4
NPPA
PTPRT

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-22496669-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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