Article
Human gene-centered transcription factor networks for enhancers and disease variants.
Cell - 23 Apr 2015
Fuxman Bass Juan I, Sahni Nidhi, Shrestha Shaleen, Garcia-Gonzalez Aurian, Mori Akihiro, Bhat Numana, Yi Song, Hill David E, Vidal Marc, Walhout Albertha J M
Abstract excerpt
Gene regulatory networks (GRNs) comprising interactions between transcription factors (TFs) and regulatory loci control development and physiology. Numerous disease-associated mutations have been identified, the vast majority residing in non-coding regions of the genome. As current GRN mapping me...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
