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Article

Role of the MMP9 gene in hemorrhagic transformations after tissue-type plasminogen activator treatment in stroke patients.

Stroke - 1 May 2012

Fernández-Cadenas Israel, Del Río-Espínola Alberto, Carrera Caty, Domingues-Montanari Sophie, Mendióroz Maite, Delgado Pilar, Rosell Anna, Ribó Marc, Giralt Dolors, Quintana Manolo, Castellanos Mar, Obach Victor, Martínez Sergi, Freijo Mari Mar, Jiménez-Conde Jordi, Roquer Jaume, Martí-Fábregas Joan, Molina Carlos A, Alvarez-Sabín José, Montaner Joan

Abstract excerpt

BACKGROUND AND PURPOSE: Despite the benefits of tissue-type plasminogen activator treatment, some stroke patients experience adverse hemorrhagic transformations (HT). Plasma protein levels of MMP9 have been associated with HT occurrence. We aimed to analyze the association of the MMP9 gene with HT occurrence. METHODS: We analyzed the MMP9 gene in blood samples from 885 stroke patients treated with tissue-type...

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Source

Identifiers

PMID: 22496335
DOI: 10.1161/STROKEAHA.111.639823

Genes

MMP9

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Role of the MMP9 gene in hemorrhagic transformations after tissue-type plasminogen activator treatment in stroke patients.PMID 22496335Read ↗

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