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Postnatal development- and age-related changes in DNA-methylation patterns in the human genome

11 Apr 2012

Abstract excerpt

Alterations in DNA methylation have been reported to occur during development and aging; however, much remains to be learned regarding post-natal and age-associated epigenome dynamics, and few if any investigations have compared human methylome patterns on a whole genome basis in cells from newborns and adults. The aim of this study was to reveal genomic regions with distinct structure and sequence...

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PMID: 22495928
DOI: 10.1093/nar/gks312

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