Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Whole-genome methylation analysis of aging human tissues identifies age-related changes in developmental and neurological pathways.

Aging cell - 1 Jul 2023

Tharakan Ravi, Ubaida-Mohien Ceereena, Dunn Christopher, Kaileh Mary, Tryggvadottir Rakel, Zukley Linda, Chia Chee W, Sen Ranjan, Ferrucci Luigi

Abstract excerpt

Age-associated changes in the DNA methylation state can be used to assess the pace of aging. However, it is not understood what mechanisms drive these changes and whether these changes affect the development of aging phenotypes and the aging process in general. This study was aimed at gaining a more comprehensive understanding of aging-related methylation changes across the whole genome, and relating these...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Aging
Share to CpG Islands

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to DNA Methylation

Share to Epigenesis, Genetic

Share to Genome

Share to Phenotype

Share to Protein Processing, Post-Translational

Source

Open in PubMed Open full text

Identifiers

PMID: 37309088
DOI: 10.1111/acel.13847
PMCID: PMC10352543

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Whole-genome methylation analysis of aging human tissues identifies age-related changes in developmental and neurological pathways.PMID 37309088Read ↗

Meta-analysis of genome-wide DNA methylation and integrative OMICs in human skeletal muscleSemantic proximity Read ↗

Epigenetic genome-wide association methylation in aging and longevity.Semantic proximity Read ↗

Epigenetic aging of classical monocytes from healthy individualsSemantic proximity Read ↗

Genome-wide multi-layered epigenomic profiling across human agingSemantic proximity Read ↗

Epigenetic influences on aging: a longitudinal genome-wide methylation study in old Swedish twinsSemantic proximity Read ↗

Integrative epigenetics and transcriptomics identify aging genes in human bloodSemantic proximity Read ↗

Early life DNA methylation profiles are indicative of age-related transcriptome changesSemantic proximity Read ↗

Progress on the role of DNA methylation in aging and longevitySemantic proximity Read ↗

Age-Related DNA Methylation Changes: Potential Impact on Skeletal Muscle Aging in HumansSemantic proximity Read ↗

Cross-sectional and longitudinal changes in DNA methylation with age: an epigenome-wide analysis revealing over 60 novel age-associated CpG sites.Semantic proximity Read ↗

Epigenetic influences on aging: a longitudinal genome-wide methylation study in old Swedish twinsSemantic proximity Read ↗

Epigenetic signature of human immune aging: the GESTALT studySemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.