Article
Association of genetic variants of human telomerase with colorectal polyps and colorectal cancer risk.
Molecular carcinogenesis - 1 Oct 2012
Hofer Philipp, Baierl Andreas, Bernhart Kathrin, Leeb Gernot, Mach Karl, Micksche Michael, Gsur Andrea
Abstract excerpt
Human telomerase reverse transcriptase (TERT) gene encodes the catalytic subunit of telomerase and is located on chromosome 5p15, a genomic region which was found to be associated with multiple cancer types. But no associations with colorectal cancer (CRC) have been reported until recently. Therefore, the purpose of this study was to investigate the influence of seven single-nucleotide polymorphisms (SNPs) of...
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