Article
MNS16A tandem repeats minisatellite of human telomerase gene: a risk factor for colorectal cancer.
Carcinogenesis - 1 Jun 2011
Hofer Philipp, Baierl Andreas, Feik Elisabeth, Führlinger Gerhard, Leeb Gernot, Mach Karl, Holzmann Klaus, Micksche Michael, Gsur Andrea
Abstract excerpt
Telomerase reactivation and expression of human telomerase gene [human telomerase reverse transcriptase (hTERT)] are hallmarks of unlimited proliferation potential of cancer cells. A polymorphic tandem repeats minisatellite of hTERT gene, termed MNS16A was reported to influence hTERT expression. To assess the role of MNS16A as potential biomarker for colorectal cancer (CRC), we investigated for the first time the...
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