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Article

The TERT variant rs2736100 is associated with colorectal cancer risk.

British journal of cancer - 4 Sept 2012

Kinnersley B, Migliorini G, Broderick P, Whiffin N, Dobbins S E, Casey G, Hopper J, Sieber O, Lipton L, Kerr D J, Dunlop M G, Tomlinson I Pm, Houlston R S

Abstract excerpt

BACKGROUND: Polymorphic variation at the 5p15.33 (TERT-CLPTM1L) locus is associated with the risk of many cancers but a relationship with colorectal cancer (CRC) risk has yet to be defined. METHODS: We used data from six genome-wide association studies (GWAS) of CRC, linkage disequilibrium mapping and imputation, to examine the relationship between 73 single-nucleotide polymorphisms at 5p15.33 and CRC risk in...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 22878375
DOI: 10.1038/bjc.2012.329
PMCID: PMC3464867

Genes

TERT

Provenance

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