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TERT Gene rs2736100 and rs2736098 Polymorphisms are Associated with Increased Cancer Risk: A Meta-Analysis.

Biochemical genetics - 1 Feb 2022

Zhang Xinyu, Chen Yan, Yan Donglin, Han Jing, Zhu Longbiao

Abstract excerpt

Abnormal telomerase activity plays a key role in the development of carcinogenesis. The variants rs2736100 and rs2736098 of the telomerase reverse transcriptase (TERT) gene, which encodes the telomerase catalytic subunit, are associated with the risk of different types of cancers. However, the results remain controversy. We conducted a meta-analysis to more precisely assess this association. We comprehensively...

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PMID: 34181135
DOI: 10.1007/s10528-021-10097-0

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 3 Sept 2026.

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