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Association of hTERT Gene Polymorphism and Colorectal Cancer (CRC) Risk in the Chinese Han Population.

The Tohoku journal of experimental medicine - 28 Jun 2024

Fu Xianxian, Xiong Yanyan, Tang Renjin, Li Xuelin, Liu Hong, Ren Xiaowei

Abstract excerpt

The catalytic subunit telomerase reverse transcriptase (hTERT) is a prerequisite for malignant transformation of human cells. Colorectal cancer (CRC) is a common malignant tumor. The genetic association of hTERT gene rs2853669 and rs2736098 polymorphisms with CRC was surveyed in the Chinese population. Two hundreds patients with CRC and 200 healthy controls were taken for blood sample collection. Sanger...

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PMID: 38296486
DOI: 10.1620/tjem.2024.J008

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