Association of telomerase reverse transcriptase gene rs10069690 variant with cancer risk: an updated meta-analysis.

doi:10.1186/s12885-024-12833-2

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Article

Association of telomerase reverse transcriptase gene rs10069690 variant with cancer risk: an updated meta-analysis.

BMC cancer - 27 Aug 2024

Zhou Chao, Yang Yunke, Shen Lu, Wang Lu, Zhang Juan, Wu Xi

Abstract excerpt

OBJECTIVE: Existing evidence suggests telomerase activation is a crucial step in tumorigenesis. The telomerase reverse transcriptase (TERT), encoded by the human TERT gene, is critical for telomerase expression. The TERT rs10069690 (C > T) variant was identified to be associated with the risk of cancer, however, there have been inconsistent results. Therefore, we performed a comprehensive meta-analysis aiming to...

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PMID: 39192222
DOI: 10.1186/s12885-024-12833-2
PMCID: PMC11350973

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TERT

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