Respiratory cytology in the era of molecular diagnostics: a review.

doi:10.1002/dc.22858

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Article

Respiratory cytology in the era of molecular diagnostics: a review.

Diagnostic cytopathology - 1 Jun 2012

Witt Benjamin L, Wallander Michelle L, Layfield Lester J, Hirschowitz Sharon

Abstract excerpt

Carcinoma of the lungs remains one of the primary causes of cancer mortality in the United States and represents a significant diagnostic challenge. Current diagnostic protocols depend substantially on cytology as an initial diagnostic modality. Pulmonary cytology can be diagnostically challenging with false positive and false negative diagnoses being relatively frequent. False positive diagnoses remain a...

Topics

Anaplastic Lymphoma Kinase
Biomarkers, Tumor
Carcinoma, Squamous Cell
Cell Nucleus
DNA Mutational Analysis
Early Detection of Cancer
ErbB Receptors
Gene Rearrangement
Humans
Lung Neoplasms
Mutation
Prognosis
Proto-Oncogene Proteins
Proto-Oncogene Proteins p21(ras)
Receptor Protein-Tyrosine Kinases
Sensitivity and Specificity
ras Proteins

Source

Open in PubMed

Identifiers

PMID: 22619130
DOI: 10.1002/dc.22858

Genes

ALK
EGFR

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026.

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