Article
ALK and ROS1 testing on lung cancer cytologic samples: Perspectives.
Cancer cytopathology - 1 Nov 2017
Pisapia Pasquale, Lozano Maria D, Vigliar Elena, Bellevicine Claudio, Pepe Francesco, Malapelle Umberto, Troncone Giancarlo
Abstract excerpt
Cytologic sampling is the mainstay of diagnosing advanced lung cancer. Moreover, to select patients for personalized first-line or second-line treatment, epidermal growth factor receptor (EGFR) mutations and anaplastic lymphoma kinase (ALK) and c-ros oncogene 1 (ROS1) rearrangements are tested on cytologic preparations. Commercially available fluorescence in situ hybridization (FISH) and immunocytochemistry (ICC)...
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