Article
No associations found between the genes situated at 6p22.1, HIST1H2BJ, PRSS16, and PGBD1 in Japanese patients diagnosed with schizophrenia.
American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics - 1 Jun 2012
Kitazawa Maiko, Ohnuma Tohru, Takebayashi Yuto, Shibata Nobuto, Baba Hajime, Ohi Kazutaka, Yasuda Yuka, Nakamura Yukako, Aleksic Branko, Yoshimi Akira, Okochi Tomo, Ikeda Masashi, Naitoh Hiroshi, Hashimoto Ryota, Iwata Nakao, Ozaki Norio, Takeda Masatoshi, Arai Heii
Abstract excerpt
Recent GWAS demonstrated an association between candidate genes located at region 6p22.1 and schizophrenia. This region has been reported to house certain candidate SNPs, which may be associated with schizophrenia at HIST1H2BJ, PRSS16, and PGBD1. These genes may presumably be associated with pathophysiology in schizophrenia, namely epigenetics and psychoneuroimmunology. A three-step study was undertaken to focus...
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