Article
The relationship between single nucleotide polymorphisms in 5-HT2A signal transduction-related genes and the response efficacy to selective serotonin reuptake inhibitor treatments in Chinese patients with major depressive disorder.
Genetic testing and molecular biomarkers - 1 Jul 2012
Li Heng-Fen, Yu Xue, Yang Kun, He Cha-Ye, Kou Shao-Jie, Cao Su-Xia, Xie Guang-Rong
Abstract excerpt
OBJECTIVE: To explore the possible relationship between six single nucleotide polymorphisms (SNPs) (rs6311 and rs6305 of 5-HT2A, rs5443 of Gβ3, rs2230739 of ACDY9, rs1549870 of PDE1A and rs255163 of CREB1, which are all related with 5-HT2A the signal transduction pathway) and the response efficac...