Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

A low-cost exon capture method suitable for large-scale screening of genetic deafness by the massively-parallel sequencing approach.

Genetic testing and molecular biomarkers - 1 Jun 2012

Tang Wenxue, Qian Dong, Ahmad Shoeb, Mattox Douglas, Todd N Wendell, Han Harrison, Huang Shouting, Li Yuhua, Wang Yunfeng, Li Huawei, Lin Xi

Abstract excerpt

Current major barriers for using next-generation sequencing (NGS) technologies in genetic mutation screening on an epidemiological scale appear to be the high accuracy demanded by clinical applications and high per-sample cost. How to achieve high efficiency in enriching targeted disease genes wh...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Computational Biology
Share to Deafness
Share to Exons

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Gene Targeting

Share to Genetic Testing

Share to High-Throughput Nucleotide Sequencing

Share to Infant, Newborn

Share to Mass Screening

Source

Open in PubMed Open full text

Identifiers

PMID: 22480152
DOI: 10.1089/gtmb.2011.0187
PMCID: PMC3378026

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-22480152-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

A low-cost exon capture method suitable for large-scale screening of genetic deafness by the massively-parallel sequencing approach.PMID 22480152Read ↗

Applications of targeted gene capture and next-generation sequencing technologies in studies of human deafness and other genetic disabilities.Semantic proximity Read ↗

A sensitive and specific diagnostic test for hearing loss using a microdroplet PCR-based approach and next generation sequencing.Semantic proximity Read ↗

A next-generation sequencing gene panel (MiamiOtoGenes) for comprehensive analysis of deafness genes.Semantic proximity Read ↗

Targeted exon sequencing successfully discovers rare causative genes and clarifies the molecular epidemiology of Japanese deafness patients.Semantic proximity Read ↗

Targeted genomic capture and massively parallel sequencing to identify novel variants causing Chinese hereditary hearing loss.Semantic proximity Read ↗

Illumina sequencing of 15 deafness genes using fragmented amplicons.Semantic proximity Read ↗

Screening of deafness-causing DNA variants that are common in patients of European ancestry using a microarray-based approach.Semantic proximity Read ↗

Dependable and efficient clinical utility of target capture-based deep sequencing in molecular diagnosis of retinitis pigmentosa.Semantic proximity Read ↗

Improved genetic testing for monogenic diabetes using targeted next-generation sequencing.Semantic proximity Read ↗

Advancing genetic testing for deafness with genomic technology.Semantic proximity Read ↗

High-performance single-chip exon capture allows accurate whole exome sequencing using the Illumina Genome Analyzer.Semantic proximity Read ↗

Massively parallel DNA sequencing successfully identifies new causative mutations in deafness genes in patients with cochlear implantation and EAS.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.