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Article

Improved genetic testing for monogenic diabetes using targeted next-generation sequencing.

Diabetologia - 1 Sept 2013

Ellard S, Lango Allen H, De Franco E, Flanagan S E, Hysenaj G, Colclough K, Houghton J A L, Shepherd M, Hattersley A T, Weedon M N, Caswell R

Abstract excerpt

AIMS/HYPOTHESIS: Current genetic tests for diagnosing monogenic diabetes rely on selection of the appropriate gene for analysis according to the patient's phenotype. Next-generation sequencing enables the simultaneous analysis of multiple genes in a single test. Our aim was to develop a targeted next-generation sequencing assay to detect mutations in all known MODY and neonatal diabetes genes. METHODS: We...

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Share to Diabetes and associated disorders
Share to Diabetes Mellitus, Type 2

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Genetic Testing

Share to Genomics and Rare Diseases

Share to High-Throughput Nucleotide Sequencing

Share to Infant, Newborn

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Share to Pancreatic function and diabetes

Source

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Identifiers

PMID: 23771172
DOI: 10.1007/s00125-013-2962-5
PMCID: PMC3737433

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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