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Article

Illumina sequencing of 15 deafness genes using fragmented amplicons.

BMC research notes - 9 Aug 2014

Van Nieuwerburgh Filip, De Keulenaer Sarah, De Schrijver Joachim, Vandesompele Jo, Van Criekinge Wim, Coucke Paul J, Deforce Dieter

Abstract excerpt

BACKGROUND: Resequencing of deafness related genes using GS FLX massive parallel sequencing of PCR amplicons spanning selected genes has previously been reported as a successful strategy to discover causal variants. The amplicon lengths were designed to be smaller than the sequencing read length of GS FLX technology, but are longer than Illumina sequencing technology read lengths. Fragmentation is thus required...

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Identifiers

PMID: 25106482
DOI: 10.1186/1756-0500-7-509
PMCID: PMC4266979

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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