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Article

Massively parallel DNA sequencing successfully identifies new causative mutations in deafness genes in patients with cochlear implantation and EAS.

PloS one - 1 Jan 2013

Miyagawa Maiko, Nishio Shin-ya, Ikeda Takuo, Fukushima Kunihiro, Usami Shin-ichi

Abstract excerpt

Genetic factors, the most common etiology in severe to profound hearing loss, are one of the key determinants of Cochlear Implantation (CI) and Electric Acoustic Stimulation (EAS) outcomes. Satisfactory auditory performance after receiving a CI/EAS in patients with certain deafness gene mutations indicates that genetic testing would be helpful in predicting CI/EAS outcomes and deciding treatment choices. However,...

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Source

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Identifiers

PMID: 24130743
DOI: 10.1371/journal.pone.0075793
PMCID: PMC3794008

Genes

ACTG1
GJB2
TECTA
TMPRSS3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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