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Article

CUP-1 is a novel protein involved in dietary cholesterol uptake in Caenorhabditis elegans.

PloS one - 1 Jan 2012

Valdes Victor J, Athie Alejandro, Salinas Laura S, Navarro Rosa E, Vaca Luis

Abstract excerpt

Sterols transport and distribution are essential processes in all multicellular organisms. Survival of the nematode Caenorhabditis elegans depends on dietary absorption of sterols present in the environment. However the general mechanisms associated to sterol uptake in nematodes are poorly understood. In the present work we provide evidence showing that a previously uncharacterized transmembrane protein,...

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Identifiers

PMID: 22479487
DOI: 10.1371/journal.pone.0033962
PMCID: PMC3313951

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