Article
Estimating fitness by competition assays between drug susceptible and resistant Mycobacterium tuberculosis of predominant lineages in Mumbai, India.
PloS one - 1 Jan 2012
Bhatter Purva, Chatterjee Anirvan, D'souza Desiree, Tolani Monica, Mistry Nerges
Abstract excerpt
BACKGROUND: Multi Drug Resistant Tuberculosis (MDR TB) is a threat to global tuberculosis control. A significant fitness cost has been associated with DR strains from specific lineages. Evaluation of the influence of the competing drug susceptible strains on fitness of drug resistant strains may have an important bearing on understanding the spread of MDR TB. The aim of this study was to evaluate the fitness of...
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