Article
Fitness of Mycobacterium tuberculosis strains of the W-Beijing and Non-W-Beijing genotype.
PloS one - 16 Apr 2010
von Groll Andrea, Martin Anandi, Stehr Matthias, Singh Mahavir, Portaels Françoise, da Silva Pedro Eduardo Almeida, Palomino Juan Carlos
Abstract excerpt
BACKGROUND: Multidrug resistant tuberculosis (MDR-TB) is a major threat for global tuberculosis control. The W-Beijing Mycobacterium tuberculosis genotype has been associated with drug resistance. Elucidation of the mechanisms underlying this epidemiological finding may have an important role in the control of MDR-TB. The aim of this study was to evaluate the fitness of drug-susceptible and MDR M. tuberculosis...
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