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Article

Fitness of drug resistant Mycobacterium tuberculosis and the impact on the transmission among household contacts.

Tuberculosis (Edinburgh, Scotland) - 1 Dec 2014

Morcillo Nora S, Imperiale Belén R, Di Giulio Ángela, Zumárraga Martín J, Takiff Howard, Cataldi Ángel A

Abstract excerpt

There has been an on-going debate on whether the development of drug resistance in Mycobacterium tuberculosis reduces its relative fitness and its ability to cause disease. The aim of this study was to explore this relationship. For this purpose, we evaluated the in vitro growth of clinical isolates and the transmission of the strains within the patients' households. Clinical and epidemiological data from...

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Source

Identifiers

PMID: 25306497
DOI: 10.1016/j.tube.2014.08.003

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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