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Article

The predictive capacity of personal genome sequencing.

Science translational medicine - 9 May 2012

Roberts Nicholas J, Vogelstein Joshua T, Parmigiani Giovanni, Kinzler Kenneth W, Vogelstein Bert, Velculescu Victor E

Abstract excerpt

New DNA sequencing methods will soon make it possible to identify all germline variants in any individual at a reasonable cost. However, the ability of whole-genome sequencing to predict predisposition to common diseases in the general population is unknown. To estimate this predictive capacity, we use the concept of a "genometype." A specific genometype represents the genomes in the population conferring a...

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Share to Genome, Human
Share to High-Throughput Nucleotide Sequencing

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 22472521
DOI: 10.1126/scitranslmed.3003380
PMCID: PMC3741669

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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