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Article

Genome-scale metabolic reconstructions of Pichia stipitis and Pichia pastoris and in silico evaluation of their potentials.

BMC systems biology - 4 Apr 2012

Caspeta Luis, Shoaie Saeed, Agren Rasmus, Nookaew Intawat, Nielsen Jens

Abstract excerpt

BACKGROUND: Pichia stipitis and Pichia pastoris have long been investigated due to their native abilities to metabolize every sugar from lignocellulose and to modulate methanol consumption, respectively. The latter has been driving the production of several recombinant proteins. As a result, significant advances in their biochemical knowledge, as well as in genetic engineering and fermentation methods have been...

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PMID: 22472172
DOI: 10.1186/1752-0509-6-24
PMCID: PMC3364918

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