Article
Effect of interleukin-18 gene polymorphisms on sensitization to wheat flour in bakery workers.
Journal of Korean medical science - 1 Apr 2012
Kim Seung-Hyun, Hur Gyu-Young, Jin Hyun Jung, Choi Hyunna, Park Hae-Sim
Abstract excerpt
Lower respiratory symptoms in bakery workers may be induced by wheat flour and endotoxins. We hypothesized that endotoxins from wheat flour may stimulate innate immunity and that interleukin-18 (IL-18) gene polymorphisms may affect their regulatory role in innate immune responses to endotoxins. To investigate the genetic contribution of IL-18 to sensitization to wheat flour, we performed a genetic association...
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