Article
Genome-wide identification of structural variants in genes encoding drug targets: possible implications for individualized drug therapy.
Pharmacogenetics and genomics - 1 Jul 2012
Rasmussen Henrik Berg, Dahmcke Christina Mackeprang
Abstract excerpt
OBJECTIVE: The objective of the present study was to identify structural variants of drug target-encoding genes on a genome-wide scale. We also aimed at identifying drugs that are potentially amenable for individualization of treatments based on knowledge about structural variation in the genes encoding their targets. METHODS: Information about human drug targets of all therapeutic drugs and nutraceuticals...
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