Article
Impact of elastin incorporation into electrochemically aligned collagen fibers on mechanical properties and smooth muscle cell phenotype.
Biomedical materials (Bristol, England) - 17 Mar 2016
Nguyen Thuy-Uyen, Bashur Chris A, Kishore Vipuil
Abstract excerpt
Application of tissue-engineered vascular grafts (TEVGs) for the replacement of small-diameter arteries is limited due to thrombosis and intimal hyperplasia. Previous studies have attempted to address the limitations of TEVGs by developing scaffolds that mimic the composition (collagen and elastin) of native arteries to better match the mechanical properties of the graft with the native tissue. However, most...
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