Article
Engineered small diameter vascular grafts by combining cell sheet engineering and electrospinning technology.
Acta biomaterialia - 1 Apr 2015
Ahn Hyunhee, Ju Young Min, Takahashi Hironobu, Williams David F, Yoo James J, Lee Sang Jin, Okano Teruo, Atala Anthony
Abstract excerpt
Tissue engineering offers an attractive approach to creating functional small-diameter (<5mm) blood vessels by combining autologous cells with a natural and/or synthetic scaffold under suitable culture conditions, which results in a tubular construct that can be implanted in vivo. We have previously developed a vascular scaffold fabricated by electrospinning poly(ε-caprolactone) (PCL) and type I collagen that...
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