Article
Highly aligned core-shell structured nanofibers for promoting phenotypic expression of vSMCs for vascular regeneration.
Nanoscale - 15 Sept 2016
Yuan Huihua, Qin Jinbao, Xie Jing, Li Biyun, Yu Zhepao, Peng Zhiyou, Yi Bingcheng, Lou Xiangxin, Lu Xinwu, Zhang Yanzhong
Abstract excerpt
This study was designed to assess the efficacy of hyaluronan (HA) functionalized well-aligned nanofibers of poly-l-lactic acid (PLLA) in modulating the phenotypic expression of vascular smooth muscle cells (vSMCs) for blood vessel regeneration. Highly aligned HA/PLLA nanofibers in core-shell structure were prepared using a novel stable jet electrospinning approach. Formation of a thin HA-coating layer atop each...
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