Article
Deciphering the molecular bases of the biological effects of antibodies against Interleukin-2: a versatile platform for fine epitope mapping.
Immunobiology - 1 Jan 2013
Rojas Gertrudis, Pupo Amaury, Leon Kalet, Avellanet Janet, Carmenate Tania, Sidhu Sachdev
Abstract excerpt
Elucidating the network of interactions established by Interleukin-2 is a key step to understanding its role as a master regulator of the immune system. Binding of this cytokine by specific antibodies gives rise to different classes of immune complexes that boost or inhibit immune responses. The...
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