Article
Development of a simple method for detection of the HLA-A*31:01 allele.
Drug metabolism and pharmacokinetics - 1 Jan 2013
Uchiyama Kazuki, Kubota Fumika, Ariyoshi Noritaka, Matsumoto Jun, Ishii Itsuko, Kitada Mitsukazu
Abstract excerpt
It is known that rare but severe cutaneous adverse drug reactions (cADRs), such as Stevens-Johnson syndrome (SJS), toxic epidermal necrolysis (TEN) and drug-induced hypersensitivity syndrome (DIHS), are induced by carbamazepine (CBZ). Recent studies have shown an association between HLA-A*31:01 a...
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