Development of a simple genotyping method for the HLA-A*31:01-tagging SNP in Japanese.

doi:10.2217/pgs.15.115

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Article

Development of a simple genotyping method for the HLA-A*31:01-tagging SNP in Japanese.

Pharmacogenomics - 1 Jan 2015

Maekawa Keiko, Nakamura Ryosuke, Kaniwa Nahoko, Mizusawa Seiho, Kitamoto Aya, Kitamoto Takuya, Ukaji Maho, Matsuzawa Yumiko, Sugiyama Emiko, Uchida Yoshimi, Kurose Kouichi, Ueta Mayumi, Sotozono Chie, Ikeda Hiroko, Yagami Akiko, Matsukura Setsuko, Kinoshita Shigeru, Muramatsu Masaaki, Ikezawa Zenro, Sekine Akihiro, Furuya Hirokazu, Takahashi Yukitoshi, Matsunaga Kayoko, Aihara Michiko, Saito Yoshiro

Abstract excerpt

AIM: To construct a simple, low-cost typing method for the surrogate marker of HLA-A*31:01, a risk factor for carbamazepine (CBZ) related Stevens-Johnson syndrome/toxic epidermal necrolysis (SJS/TEN). MATERIALS & METHODS: DNAs from Japanese SJS/TEN patients were used for genotyping and developing the assay. RESULTS: HLA-A*31:01 was confirmed to be significantly associated with definite/probable cases of...

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PMID: 26490229
DOI: 10.2217/pgs.15.115

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

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