Article
CD25 is expressed by canine cutaneous mast cell tumors but not by cutaneous connective tissue mast cells.
Veterinary pathology - 1 Nov 2012
Meyer A, Gruber A D, Klopfleisch R
Abstract excerpt
Canine cutaneous mast cell tumors (MCT) of different histological grades have distinct biological behaviors. However, little is known about underlying molecular mechanisms that lead to tumor development and increasing malignancy with higher tumor grade. Recent studies have identified the interleukin-2 receptor (IL-2R) subunits CD25 and CD2 as markers that distinguish nonneoplastic from neoplastic mast cells in...
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