Article
Does the aberrant expression of CD2 and CD25 by skin mast cells truly correlate with systemic involvement in patients presenting with mastocytosis in the skin?
International archives of allergy and immunology - 1 Jan 2014
Lange Magdalena, Żawrocki Anton, Nedoszytko Bogusław, Wasąg Bartosz, Niedoszytko Marek, Jassem Ewa, Nowicki Roman, Żmijewski Michał A, Biernat Wojciech
Abstract excerpt
BACKGROUND: Neoplastic mast cells involving the bone marrow (BMMCs) of patients with mastocytosis display an aberrant expression of CD25 and/or CD2 antigens. The aim of this study was to determine the frequency of CD2 and CD25 expression on skin mast cells (sMCs) of patients with mastocytosis in the skin at the early stage of the disease. Furthermore, the usefulness of the phenotypic profile of sMCs for the...
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