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Article

Controversial role of mast cells in skin cancers

15 Jun 2016

Abstract excerpt

Cancer development is a multistep process characterized by genetic and epigenetic alterations during tumor initiation and progression. The stromal microenvironment can promote tumor development. Mast cells, widely distributed throughout all tissues, are a stromal component of many solid and haematologic tumors. Mast cells can be found in human and mouse models of skin cancers such as melanoma, basal and squamous...

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PMID: 27305467
DOI: 10.1111/exd.13107

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