Article
Association between the angiotensin-converting enzyme gene insertion/deletion polymorphism and first-episode patients with schizophrenia in a Chinese Han population.
Human psychopharmacology - 1 May 2014
Hui Li, Wu Jing Qin, Zhang Xuan, Lv Jie, Du Wei Li, Kou Chang Gui, Yu Ya Qin, Lv Meng Han, Chen Da Chun, Zhang Xiang Yang
Abstract excerpt
BACKGROUND: Angiotensin-converting enzyme (ACE), a key enzyme of the renin-angiotensin system, can modulate dopamine turnover in the midbrain. Previous studies have revealed an association between ACE gene insertion/deletion (I/D) polymorphism and chronic schizophrenia, yet results are conflicting. OBJECTIVE: The primary objective of this study was to examine whether the ACE gene I/D polymorphism is associated...
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