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Article

Association of CASP7 polymorphisms and survival of patients with non-small cell lung cancer with platinum-based chemotherapy treatment.

Chest - 1 Sept 2012

Qian Ji, Gu Shaohua, Wu Qihan, Zhao Xueying, Wu Wenting, Gao Zhiqiang, Zhang Wei, Tan Xiaoming, Wang Haijian, Wang Jiucun, Fan Weiwei, Chen Hongyan, Han Baohui, Lu Daru, Wei Qingyi, Jin Li

Abstract excerpt

BACKGROUND: CASP7 plays a crucial role in cancer development and chemotherapy efficacy. We, therefore, explored whether single nucleotide polymorphisms (SNPs) of the CASP7 gene can modulate outcomes of patients with advanced non-small cell lung cancer (NSCLC) treated with first-line platinum-based chemotherapy. METHODS: We systematically genotyped 17 SNPs of CASP7 first in a discovery set of 279 patients with...

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Identifiers

PMID: 22441531
DOI: 10.1378/chest.11-2522

Genes

CASP7

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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