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Article

Caspase 8 polymorphisms contribute to the prognosis of advanced lung adenocarcinoma patients after platinum-based chemotherapy.

Cancer biology & therapy - 2 Dec 2017

Liu Di, Xu Wen, Ding Xi, Yang Yang, Lu Yanlin, Fei Ke, Su Bo

Abstract excerpt

Lung cancer is the leading cause of cancer deaths in China, and about 60% of the cases are diagnosed with histological adenocarcinoma. The caspase 8 (CASP8) gene is a critical initiator of the extrinsic apoptosis pathway. To explore the relationship between tagSNPs or haplotypes of CASP8 and the efficacy of platinum-based chemotherapy in advanced lung adenocarcinoma patients of China, we recruited 555 advanced...

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Identifiers

PMID: 28278082
DOI: 10.1080/15384047.2016.1276128
PMCID: PMC5718808

Genes

CASP8

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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