Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

The HIF1A C85T single nucleotide polymorphism influences the number of branches of the human coronary tree.

Cardiology - 1 Jan 2012

Duran Joan, Götzens Víctor, Carballo Julio, Martín Eva, Petit Màrius, Cordero Alex, Sánchez Olavarría María Pilar, Reig Josep, de Anta Josep Maria

Abstract excerpt

OBJECTIVES: Hypoxia is required for the development of the cardiovascular system. Tissue adaptation to low oxygen is mediated through hypoxia-inducible factor 1. Hypoxia-driven gradients of vascular endothelial growth factor within the heart drive vessel tip sprouting and the angiogenic phase of vasculogenesis. We hypothesized that functional variants of the HIF1A C85T single nucleotide polymorphism (SNP) are...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Aged
Share to Coronary Angiography

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Coronary Vessels

Share to Genotype

Share to Hypoxia-Inducible Factor 1, alpha Subunit

Share to Neovascularization, Physiologic

Share to Polymorphism, Single Nucleotide

Share to Young Adult

Source

Identifiers

PMID: 22441426
DOI: 10.1159/000336818

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

The HIF1A C85T single nucleotide polymorphism influences the number of branches of the human coronary tree.PMID 22441426Read ↗

Hypoxia-inducible factor-1α polymorphisms link to coronary artery collateral development and clinical presentation of coronary artery disease.Semantic proximity Read ↗

Heterogeneity and Differentiation of the Human Arterial Tree: Focus on microRNA Expression in Vascular Frail PatientsSemantic proximity Read ↗

Plasma levels of soluble VEGF receptor isoforms, circulating pterins and VEGF system SNPs as prognostic biomarkers in patients with acute coronary syndromes.Semantic proximity Read ↗

Genetic association study of coronary collateral circulation in patients with coronary artery disease using 22 single nucleotide polymorphisms corresponding to 10 genes involved in postischemic neovascularization.Semantic proximity Read ↗

The influence of genotype on vascular endothelial growth factor and regulation of myocardial collateral blood flow in patients with acute and chronic coronary heart disease.Semantic proximity Read ↗

The ABO Locus is Associated with Increased Fibrin Network Formation in Patients with Stable Coronary Artery Disease.Semantic proximity Read ↗

GCH1 haplotype determines vascular and plasma biopterin availability in coronary artery disease effects on vascular superoxide production and endothelial function.Semantic proximity Read ↗

Study on the role of environmental parameters and HIF-1A gene polymorphism in coronary collateral formation among patients with ischemic heart disease.Semantic proximity Read ↗

Vascular endothelial growth factor-A promoter polymorphisms, circulating VEGF-A and survival in acute coronary syndromes.Semantic proximity Read ↗

Evaluation of coronary microvascular function and nitric oxide synthase intron 4a/b polymorphism in patients with coronary slow flow.Semantic proximity Read ↗

Identifying myocardial regions perfused by coronary arteries through detailed human microvasculature dataSemantic proximity Read ↗

Functional vascular endothelial growth factor gene polymorphisms and diabetes: effect on coronary collaterals in patients with significant coronary artery disease.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.