Article
Evaluation of coronary microvascular function and nitric oxide synthase intron 4a/b polymorphism in patients with coronary slow flow.
Coronary artery disease - 1 Sept 2013
Ekmekci Ahmet, Güngör Bariş, Özcan Kazim S, Abaci Neslihan, Ilhan Erkan, Ekmekci Sema S, Kemaloğlu Tuğba, Osmonov Damirbek, Ustek Duran, Eren Mehmet
Abstract excerpt
OBJECTIVE: Slow coronary flow (SCF) is reported to be associated with increased risk of cardiovascular disease. We have used coronary flow reserve measurement by transthoracic Doppler echocardiography to determine coronary microvascular function in patients with SCF and to determine whether the intron 4a/b polymorphism of the eNOS gene influences coronary endothelial function. METHODS: Overall, 96 patients with...
Topics
- Blood Flow Velocity
- Case-Control Studies
- Chi-Square Distribution
- Coronary Angiography
- Coronary Circulation
- Coronary Vessels
- Echocardiography, Doppler, Color
- Female
- Fractional Flow Reserve, Myocardial
- Gene Frequency
- Genetic Predisposition to Disease
- Humans